Oxymorphone Tablets

Pronunciation: OX-i-MOR-fone
Generic Name: Oxymorphone
Brand Name: Opana

Oxymorphone is used for:

Treating moderate to severe pain in certain patients.

Oxymorphone is an opioid (narcotic) analgesic. It works by binding to certain receptors in the brain and nervous system to reduce pain.

Do NOT use Oxymorphone if:

• you are allergic to any ingredient in Oxymorphone or any other codeine- or morphine-related medicine (eg, morphine, codeine, oxycodone)


• you have difficult or slowed breathing, high levels of carbon dioxide in the blood, or severe asthma, or you are having an asthma attack


• you are in labor


• you have moderate to severe liver problems


• you have severe diarrhea, bowel problems caused by antibiotics or food poisoning, or certain other severe bowel problems (eg, paralytic ileus)


• you are taking sodium oxybate (GHB) or an agonist/antagonist analgesic (eg, pentazocine)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Oxymorphone:

Some medical conditions may interact with Oxymorphone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of lung or breathing problems (eg, asthma, emphysema, bronchitis, chronic obstructive pulmonary disease [COPD]), sleep apnea (you stop breathing when you sleep), curvature of the spine (eg, kyphoscoliosis), heart problems (eg, cor pulmonale), low blood pressure, dehydration, or low blood volume


• if you have severe drowsiness, a recent head injury, growths in the brain, increased pressure in the brain, or a history of seizures (eg, epilepsy)


• if you have liver or kidney problems, gallbladder or pancreas problems, adrenal gland problems (eg, Addison disease), an underactive thyroid, an enlarged prostate, a urinary blockage, or stomach or bowel problems (eg, inflammation), or if you have had recent stomach or bowel surgery.


• if you drink alcohol regularly, have symptoms of alcohol withdrawal, or have a history of suicidal thoughts or attempts


• if you have a personal or family history of mental or mood problems, alcohol abuse, or other substance abuse or dependence


• if you are in poor health or shock, are very overweight, or will be having surgery

Some MEDICINES MAY INTERACT with Oxymorphone. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Phenothiazines (eg, chlorpromazine) because the risk of low blood pressure may be increased


• Barbiturate anesthetics (eg, thiopental), cimetidine, or sodium oxybate (GHB) because the risk of severe drowsiness, coma, confusion, or slowed or difficult breathing may be increased


• Anticholinergics (eg, scopolamine, benztropine) because the risk of severe constipation or trouble urinating may be increased


• Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) because the risk of a severe reaction including fever, seizures, and coma may be increased


• Agonist/antagonist analgesics (eg, pentazocine) or naltrexone because they may decrease Oxymorphone's effectiveness and withdrawal may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Oxymorphone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Oxymorphone:

Use Oxymorphone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Oxymorphone on an empty stomach at least 1 hour before or 2 hours after eating.


• Oxymorphone must only be taken by mouth.


• If you are taking Oxymorphone for persistent pain, take it on a regular schedule to help control the pain more effectively.


• Do not change your dose or suddenly stop taking Oxymorphone without checking with your doctor.


• If Oxymorphone is no longer needed, dispose of it as soon as possible. Ask your doctor or pharmacist how to dispose of Oxymorphone properly.


• If you miss a dose of Oxymorphone and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Oxymorphone.

Important safety information:

• Oxymorphone may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol, other opiate pain medicines, or certain other medicines. Use Oxymorphone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you take Oxymorphone; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Oxymorphone may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.


• Oxymorphone may be habit forming. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Misuse or abuse of Oxymorphone may cause severe side effects, including severe breathing problems, seizures, coma, and possibly death.


• Constipation is a common side effect of Oxymorphone. Talk to your doctor about using laxatives or stool softeners to prevent or treat constipation while you use Oxymorphone.


• If your pain continues or becomes worse or if you have side effects that concern you, contact your doctor.


• Tell your doctor or dentist that you take Oxymorphone before you receive any medical or dental care, emergency care, or surgery.


• Use Oxymorphone with caution in the ELDERLY; they may be more sensitive to its effects, especially drowsiness, dizziness, confusion, and nausea.


• Oxymorphone should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Oxymorphone may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Oxymorphone while you are pregnant. It is unknown if Oxymorphone is found in breast milk. Do not breast-feed while taking Oxymorphone.

When used for long periods of time or at high doses, Oxymorphone may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Oxymorphone stops working well. Do not take more than prescribed.

Some people who use Oxymorphone for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. Dependence is unlikely to be an issue in terminally ill patients where comfort is more important. If you are taking Oxymorphone regularly, do not suddenly stop taking it without checking with your doctor. WITHDRAWAL symptoms have occurred when Oxymorphone is suddenly stopped and may include anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea and vomiting; pain; rigid muscles; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping. Contact your doctor if you notice any of these symptoms after stopping Oxymorphone.

Possible side effects of Oxymorphone:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; constipation; dizziness; drowsiness; dry mouth; gas; headache; lightheadedness; nausea; sweating; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; fainting; fast, slow, or irregular heartbeat; fever; hallucinations; mental or mood changes; seizure; severe or persistent dizziness or drowsiness; severe or persistent headache or vomiting; shallow, slowed, or difficult breathing; trouble urinating; unusual swelling; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Oxymorphone side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include bluish skin; chest pain; cold and clammy skin; coma; difficult or slow breathing; limp muscles; numbness of an arm or leg; pinpoint pupils; severe drowsiness or dizziness; slow or irregular heartbeat.

Proper storage of Oxymorphone:

Store Oxymorphone at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store Oxymorphone in the bathroom. Keep Oxymorphone out of the reach of children and away from pets.

General information:

• If you have any questions about Oxymorphone, please talk with your doctor, pharmacist, or other health care provider.


• Oxymorphone is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Oxymorphone. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Oxymorphone resources

• Oxymorphone Side Effects (in more detail)
• Oxymorphone Dosage
• Oxymorphone Use in Pregnancy & Breastfeeding
• Drug Images
• Oxymorphone Drug Interactions
• Oxymorphone Support Group
• 107 Reviews for Oxymorphone - Add your own review/rating

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Olux

Generic Name: clobetasol (Topical application route)

kloe-BAY-ta-sol PROE-pee-oh-nate

Commonly used brand name(s)

In the U.S.

• Clobevate


• Clobex


• Cormax


• Embeline


• Embeline E


• Embeline Scalp Application


• Olux


• Olux/Olux-E Complete Pack


• Olux-E


• Temovate


• Temovate E

In Canada

• Clobetasol Propionate


• Dermovate


• Dermovate Scalp Application


• Med Clobetasol Scalp Application


• Ratio-Clobetasol

Available Dosage Forms:

• Cream


• Ointment


• Gel/Jelly


• Spray


• Solution


• Foam


• Emollient Cream


• Lotion


• Shampoo

Therapeutic Class: Corticosteroid, Very Strong

Pharmacologic Class: Clobetasol

Uses For Olux

Clobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. The solution and foam are used for scalp problems, the lotion and spray are used for moderate to severe plaque psoriasis, and the shampoo is used for moderate to severe scalp psoriasis. This medicine is a corticosteroid (cortisone-like medicine or steroid).

This medicine is available only with your doctor's prescription.

Before Using Olux

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of clobetasol topical gel, foam, cream, ointment, or scalp solution in children 12 years of age and older. However, because of this medicine's toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using this medicine, follow your doctor's instructions very carefully. Safety and efficacy have not been established in children younger than 12 years of age and the use of clobetasol topical gel, foam, cream, ointment, or scalp solution is not recommended. The safety and efficacy of clobetasol topical spray, lotion, or shampoo have not been established in children and use is not recommended.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of clobetasol topical in the elderly.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Cushing's syndrome (adrenal gland disorder) or


• Diabetes or


• Hyperglycemia (high blood sugar) or


• Intracranial hypertension (increased pressure in the head)—Use with caution. May make these conditions worse.

• Infection of the skin at or near the place of application or


• Large sores, broken skin, or severe skin injury at the place of application—The chance of side effects may be increased.

• Perioral dermatitis (skin problem) or


• Rosacea (skin problem)—Should not be used in patients with these conditions.

Proper Use of clobetasol

This section provides information on the proper use of a number of products that contain clobetasol. It may not be specific to Olux. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

Do not use this medicine on the face, groin, or underarms unless directed to do so by your doctor.

To use the cream, foam, gel, lotion, ointment, or spray:

• Wash your hands with soap and water before and after using this medicine.


• Apply a thin layer of this medicine to the affected area of the skin. Rub it in gently.


• With the lotion, protect the skin from water, clothing, or anything that causes rubbing until the medicine has dried. Also, shake the lotion well before using it.


• Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.

To use the foam, scalp solution, or shampoo:

• Wash your hands with soap and water before and after using this medicine.


• Apply a thin layer of this medicine to the affected area of the scalp. Rub it in gently.


• Do not cover the scalp (e.g., shower cap, bathing cap) while it is being treated.


• Do not use the shampoo for more than 4 weeks, the foam and scalp solution for more than 2 weeks unless your doctor has told you to.

This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For redness, itching, and swelling of the skin:
  
  • For topical dosage forms (cream, gel, or ointment):
    
    • Adults—Apply to the affected area of the skin two times per day.
    
    
    • Children 12 to 17 years of age—Apply to the affected area of the skin two times per day.
    
    
    • Children younger than 12 years of age—Use is not recommended.
    
    
  
  
  • For topical dosage form (lotion):
    
    • Adults—Apply to the affected area of the skin two times per day.
    
    
    • Children—Use is not recommended.
    
    
  
  


• For plaque psoriasis:
  
  • For topical dosage form (foam):
    
    • Adults—Apply to the affected area of the skin two times per day, once in the morning and once at night.
    
    
    • Children 12 to 17 years of age—Apply to the affected area of the skin two times per day, once in the morning and once at night.
    
    
    • Children younger than 12 years of age—Use is not recommended.
    
    
  
  
  • For topical dosage form (spray):
    
    • Adults—Spray to the affected area of the skin two times per day.
    
    
    • Children—Use is not recommended.
    
    
  
  


• For scalp problems:
  
  • For topical dosage form (foam or scalp solution):
    
    • Adults—Apply to the affected area of the scalp two times per day, once in the morning and once at night.
    
    
    • Children 12 to 17 years of age—Apply to the affected area of the scalp two times per day, once in the morning and once at night.
    
    
    • Children younger than 12 years of age—Use is not recommended.
    
    
  
  
  • For topical dosage form (shampoo):
    
    • Adults—Apply to the affected area of the scalp once a day.
    
    
    • Children—Use is not recommended.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the foam can at room temperature, away from heat and direct light. Do not keep this medicine inside a car where it could be exposed to extreme heat. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Precautions While Using Olux

It is very important that your doctor check the progress of you or your child at regular visits for any unwanted effects that may be caused by this medicine.

If your or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.

Stop using this medicine and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.

Make sure your doctor knows that you are using clobetasol gel. You may need to stop using this medicine several days before having surgery.

Do not use cosmetics or other skin care products on the treated areas.

Olux Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Burning or stinging at the application site

Less common

• Burning sensation of the skin


• dry skin


• flushing or redness of the skin


• itching, scaling, severe redness, soreness, or swelling of the skin


• skin irritation


• skin rash, encrusted, scaly and oozing


• thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g. between the fingers)

Incidence not known

• Burning, itching, and pain in hairy areas, or pus at the root of the hair


• hair loss


• redness and scaling around the mouth


• thinning of the hair


• thinning, weakness, or wasting away of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Cough


• sore throat

Less common

• Burning, itching, and pain in hairy areas, or pus at the root of the hair


• changes in skin coloring


• body aches or pain


• congestion


• cough


• dryness or soreness of the throat


• fever


• headache


• hoarseness


• raised, dark red, wart-like spots on the skin, especially when used on the face


• skin discomfort


• stuffy or runny nose


• tender, swollen glands in the neck


• trouble with swallowing


• unusual tiredness or weakness


• voice changes

Incidence not known

• Acne or pimples


• burning and itching of the skin with pinhead-sized red blisters


• increased hair growth on the forehead, back, arms, and legs


• lightening of normal skin color


• lightening of treated areas of dark skin


• reddish purple lines on the arms, face, legs, trunk, or groin


• softening of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Olux side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Olux resources

• Olux Side Effects (in more detail)
• Olux Use in Pregnancy & Breastfeeding
• Olux Drug Interactions
• Olux Support Group
• 7 Reviews for Olux - Add your own review/rating

• Olux Prescribing Information (FDA)


• Olux Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Olux Concise Consumer Information (Cerner Multum)


• Clobex Lotion MedFacts Consumer Leaflet (Wolters Kluwer)


• Clobex Prescribing Information (FDA)


• Cormax Prescribing Information (FDA)


• Embeline Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Olux-E Emollient Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Olux-E Prescribing Information (FDA)


• Temovate Prescribing Information (FDA)

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Dytan-D

Generic Name: diphenhydramine and phenylephrine (DYE fen HYE dra meenand FEN il EFF rin)

Brand Names: Alahist LQ, Aldex-CT, Children's Triacting Night Time, D-Tann, Dimetapp Nighttime Cold & Congestion, Diphenmax D, Dytan-D, PediaCare Children's Allergy & Cold, Robitussin Night Time Cough & Cold, Robitussin Night Time Cough & Cold Children's, Robitussin Night Time Cough & Cold Pediatric, Triaminic Night Time Cold & Cough

What is Dytan-D (diphenhydramine and phenylephrine)?

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of diphenhydramine and phenylephrine is used to treat runny or stuffy nose, sneezing, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

Diphenhydramine and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Dytan-D (diphenhydramine and phenylephrine)?

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant. Avoid drinking alcohol while you are taking this medication. It can add to drowsiness caused by an antihistamine.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by diphenhydramine.

What should I discuss with my healthcare provider before taking Dytan-D (diphenhydramine and phenylephrine)?

You should not use this medication if you are allergic to diphenhydramine or phenylephrine.

Before taking this medication, tell your doctor if you are allergic to any drugs, or if you have:

• 
  

  asthma;

  
  


• 
  

  heart disease or high blood pressure;

  
  


• 
  

  diabetes;

  
  


• 
  

  a thyroid disorder;

  
  


• 
  

  glaucoma;

  
  


• 
  

  kidney disease;

  
  


• 
  

  an enlarged prostate; or

  
  


• 
  

  problems with urination.

  
  

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medication.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take Dytan-D (diphenhydramine and phenylephrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Make sure you chew the chewable tablet before you swallow it.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store this medicine at room temperature, away from heat, light, and moisture.

What happens if I miss a dose?

Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Dytan-D (diphenhydramine and phenylephrine)?

Avoid drinking alcohol while you are taking this medication. It can add to drowsiness caused by an antihistamine. Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by diphenhydramine.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines, decongestants, and cough suppressants are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.

Dytan-D (diphenhydramine and phenylephrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

• 
  

  fast, pounding, or uneven heartbeat;

  
  


• 
  

  confusion, hallucinations, unusual thoughts or behavior;

  
  


• 
  

  urinating less than usual or not at all;

  
  


• 
  

  severe dizziness, anxiety, restless feeling, or nervousness;

  
  


• 
  

  easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;

  
  


• 
  

  increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure); or

  
  


• 
  

  nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  

Less serious side effects may include:

• 
  

  blurred vision;

  
  


• 
  

  dry mouth;

  
  


• 
  

  nausea, stomach pain, constipation;

  
  


• 
  

  dizziness, drowsiness;

  
  


• 
  

  problems with memory or concentration;

  
  


• 
  

  ringing in your ears;

  
  


• 
  

  mild loss of appetite;

  
  


• 
  

  warmth, tingling, or redness under your skin;

  
  


• 
  

  feeling excited or restless;

  
  


• 
  

  sleep problems (insomnia); or

  
  


• 
  

  skin rash or itching.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Dytan-D (diphenhydramine and phenylephrine)?

Tell your doctor about all other medications you use, especially:

• 
  

  medicines to treat high blood pressure;

  
  


• 
  

  a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others;

  
  


• 
  

  antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others; or

  
  


• 
  

  an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).

  
  

This list is not complete and there may be other drugs that can interact with diphenhydramine and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Dytan-D resources

• Dytan-D Side Effects (in more detail)
• Dytan-D Use in Pregnancy & Breastfeeding
• Dytan-D Drug Interactions
• Dytan-D Support Group
• 0 Reviews for Dytan-D - Add your own review/rating

• Dytan-D Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Alahist LQ Liquid MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Dytan-D with other medications

• Cold Symptoms
• Hay Fever
• Sinusitis

Where can I get more information?

• Your pharmacist can provide more information about diphenhydramine and phenylephrine.

See also: Dytan-D side effects (in more detail)

Revia

Pronunciation: nal-TREX-ohn
Generic Name: Naltrexone
Brand Name: Revia

Revia can cause liver problems when given in large doses. Stop using Revia and seek immediate medical help if symptoms of liver problems develop, such as abdominal or stomach pain for more than a few days, white bowel movements, yellowing of the eyes or skin, or dark urine. Revia must not be used in patients who already have liver problems (eg, hepatitis, liver failure).

Revia is used for:

Treating alcoholism and narcotic (opioid) addiction in adults, as part of a complete treatment program. It may also be used to treat other conditions as determined by your doctor.

Revia is a narcotic antagonist. It is thought to work by blocking the effects of injectable opioids (eg, heroin, narcotic pain relievers). It has also been shown to decrease alcohol consumption.

Do NOT use Revia if:

• you are allergic to any ingredient in Revia


• you are taking narcotic medications for pain, are dependent on narcotics, are experiencing withdrawal symptoms from narcotics, have failed the challenge test with Revia, or have tested positive for narcotics


• you have hepatitis, liver failure, or liver disease

Contact your doctor or health care provider right away if any of these apply to you.

Before using Revia:

Some medical conditions may interact with Revia. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have kidney or liver problems, or a history of suicidal thoughts or behavior with or without depression

Some MEDICINES MAY INTERACT with Revia. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Narcotic analgesics (eg, codeine), narcotic cough/cold medicines, or medicines used for diarrhea because effectiveness may be decreased by Revia. Withdrawal symptoms may occur if you are physically dependent on opioid medicines.


• Thioridazine because side effects such as sleepiness and sluggishness may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Revia may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Revia:

Use Revia as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Revia may be taken with or without food.


• Revia should not be taken until the naltrexone challenge test is negative.


• Before taking Revia, you must be willing to take Revia to help with alcohol dependence, you must be free of substance abuse for 7 to 10 days, you must not have any severe or active liver or kidney problems, and you must not have any other medical problems or conditions that make taking Revia inadvisable.


• If you miss a dose of Revia and you are taking 1 dose daily, do no try to make up the missed dose by doubling the dose the next day. Take the next scheduled dose and consult your doctor.

Ask your health care provider any questions you may have about how to use Revia.

Important safety information:

• Revia may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Revia. Using Revia alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.


• Carry identification to alert health care providers that you are taking Revia. You can get a medication card from your doctor to use for this purpose.


• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Revia.


• Contact your health care provider at once if any of the following signs or symptoms of hepatitis occur while taking Revia: stomach pain lasting more than a few days; white bowel movements; dark urine; yellowing of the skin or eyes.


• Do not use narcotics while taking Revia, including opioid-containing medicines (eg, cough and cold products, pain relievers, heroin). Revia may increase your sensitivity to narcotics. Therefore, even very low doses may cause coma or be life-threatening.


• Before you have any medical or dental surgery or emergency treatments, tell the doctor or dentist that you are taking Revia.


• LAB TESTS, including liver function, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.


• Use Revia with extreme caution in CHILDREN younger than 18 years of age. Safety and effectiveness in this age group have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Revia during pregnancy. It is unknown if Revia is excreted in breast milk. If you are or will be breast-feeding while you are using Revia, check with your doctor or pharmacist to discuss the risks to your baby.

If you are addicted to narcotics and are given Revia, you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of Revia:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; appetite loss; chills; constipation; delayed ejaculation; diarrhea; dizziness; drowsiness; feeling down; headache; increased energy; increased thirst; irritability; joint and muscle pain; low energy; nausea; nervousness; sleeplessness; stomach pain/cramps; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abdominal or stomach pain; cramping; dark urine; depression; suicidal thoughts or behaviors; unusual tiredness or weakness; vomiting; white bowel movements; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Revia side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately.

Proper storage of Revia:

Store Revia at room temperature, 59 to 86 degrees F (15 to 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Revia out of the reach of children and away from pets.

General information:

• If you have any questions about Revia, please talk with your doctor, pharmacist, or other health care provider.


• Revia is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Revia. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Revia resources

• Revia Side Effects (in more detail)
• Revia Use in Pregnancy & Breastfeeding
• Drug Images
• Revia Drug Interactions
• Revia Support Group
• 3 Reviews for Revia - Add your own review/rating

• Revia Prescribing Information (FDA)


• Revia Advanced Consumer (Micromedex) - Includes Dosage Information


• Naltrexone Prescribing Information (FDA)


• Naltrexone Monograph (AHFS DI)


• Vivitrol Prescribing Information (FDA)


• Vivitrol Advanced Consumer (Micromedex) - Includes Dosage Information


• Vivitrol Consumer Overview

Compare Revia with other medications

• Alcohol Dependence
• Fibromyalgia
• Opiate Dependence
• Trichotillomania